Apoptotic agent-1
Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].
Product Specifications
CAS Number
2490538-26-4
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptotic-agent-1.html
Solubility
10 mM in DMSO
Smiles
SC1=NC(C2=CC=C([N+]([O-])=O)C=C2)=C3C(N=CN=C3Cl)=N1
Molecular Formula
C12H6ClN5O2S
Molecular Weight
319.73
References & Citations
[1]Haffez H, et al. Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity. Bioorg Chem. 2020 Nov;104:104249.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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