Apoptotic agent-1

Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].

Product Specifications

CAS Number

[2490538-26-4]

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/apoptotic-agent-1.html

Solubility

10 mM in DMSO

Smiles

SC1=NC(C2=CC=C([N+]([O-])=O)C=C2)=C3C(N=CN=C3Cl)=N1

Molecular Formula

C12H6ClN5O2S

Molecular Weight

319.73

References & Citations

[1]Haffez H, et al. Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity. Bioorg Chem. 2020 Nov;104:104249.