Anticandidal agent-1

Anticandidal agent-1 (compound c2) is a potent and broad-spectrum anticandidal agent. Anticandidal agent-1 shows anticandidal activity against C. albicans and C. glabrata, with MIC50 values of 8.65 and 13.51 μg/mL, respectively. Anticandidal agent-1 inhibits biofilm by blocking hyphal elongation and filamentation[1].

Product Specifications

CAS Number

2548852-85-1

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/anticandidal-agent-1.html

Solubility

10 mM in DMSO

Smiles

CC1=CC[C@]([C@]2(C)OC3=C(C(O)=C(C(O)=C3CC2)C=O)C=O)([H])CC1

Molecular Formula

C19H22O5

Molecular Weight

330.37

References & Citations

[1]Zhong LF, et al. Anticandidal formyl phloroglucinol meroterpenoids: Biomimetic synthesis and in vitro evaluation. Bioorg Chem. 2020 Nov;104:104248.