CYP3A4 enzyme-IN-1
CYP3A4 enzyme-IN-1 (compound 59) is a potent antibacterial agent, with a MIC of 1 μg/mL for MRSA. CYP3A4 enzyme-IN-1 exhibits low to moderate inhibitory effects on CYP1A2, CYP2E1, CYP2D6, and CYP3A4 enzymes[1].
Product Specifications
CAS Number
2531281-25-9
UNSPSC
12352005
Target
Bacterial; Cytochrome P450
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cyp3a4-enzyme-in-1.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]1[C@]23[C@](C(CC3)=O)([H])[C@]([C@@H](C[C@](C)([C@H]1O)C=C)OC(CN4CCN(CC4)C(CN5C=C(N=N5)CN6CCN(C7=CC=C(C=C7)[N+]([O-])=O)CC6)=O)=O)([C@@H](CC2)C)C
Molecular Formula
C41H58N8O7
Molecular Weight
774.95
References & Citations
[1]Zhang GY, et, al. Design, synthesis and biological evaluation of novel pleuromutilin derivatives containing piperazine and 1,2,3-triazole linker. Bioorg Chem. 2020 Dec;105:104398.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP1; CYP2; CYP3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC041081-100 1x 100 µL
CD45RO (190-2F2.5), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC941927-500 1x 500 µL
SOX9 / SRY-box 9 (PCRP-SOX9-1A2), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC742307-500 1x 500 µL
Moesin (rMSN/492), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741133-500 1x 500 µL
CD74 (CLIP/1133), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC941022-100 1x 100 µL
Hepatocyte Specific (CPS1/1022), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940532-500 1x 500 µL
Cytokeratin 14 (KRT14/532), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details