CYP3A4 enzyme-IN-1
Product Specifications
UNSPSC Description
CYP3A4 enzyme-IN-1 (compound 59) is a potent antibacterial agent, with a MIC of 1 μg/mL for MRSA. CYP3A4 enzyme-IN-1 exhibits low to moderate inhibitory effects on CYP1A2, CYP2E1, CYP2D6, and CYP3A4 enzymes[1].
Target Antigen
Bacterial; Cytochrome P450
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cyp3a4-enzyme-in-1.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]1[C@]23[C@](C(CC3)=O)([H])[C@]([C@@H](C[C@](C)([C@H]1O)C=C)OC(CN4CCN(CC4)C(CN5C=C(N=N5)CN6CCN(C7=CC=C(C=C7)[N+]([O-])=O)CC6)=O)=O)([C@@H](CC2)C)C
Molecular Weight
774.95
References & Citations
[1]Zhang GY, et, al. Design, synthesis and biological evaluation of novel pleuromutilin derivatives containing piperazine and 1,2,3-triazole linker. Bioorg Chem. 2020 Dec;105:104398.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146177/CYP3A4-enzyme-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146177/
Clinical Information
No Development Reported
CAS Number
2531281-25-9
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