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KCa1.1 channel activator-2

KCa1.1 channel activator-2 (compound 3F), a Quercetin hybrid derivative, is a selective vascular KCa1.1 channel stimulator. KCa1.1 channel activator-2 exhibits potent myorelaxant activity[1].

Product Specifications

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/kca1-1-channel-activator-2.html

Solubility

10 mM in DMSO

Smiles

O=C(OC1=CC2=C(C(O)=C1)C(C(O)=C(O2)C3=CC=C(C(O)=C3)O)=O)CCCCC4CCSS4

Molecular Formula

C23H22O8S2

Molecular Weight

490.55

References & Citations

[1]Carullo G, et, al. Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular K Ca 1.1 channel stimulators. Bioorg Chem. 2020 Dec;105:104404.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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