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FabH-IN-1

FabH-IN-1 (compound 3f) is an inhibitor of bacterial 3-oxoacyl-[acyl-carrier-protein] synthase 3 (FabH) enzyme which is a broad-spectrum antimicrobial target. FabH-IN-1 is effective against gram-positive and gram-negative. FabH-IN-1 is also a good antioxidant[1].

Product Specifications

CAS Number

2692652-49-4

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fabh-in-1.html

Solubility

10 mM in DMSO

Smiles

CC1=NC(C2=CC=C(NC3=CC=C(OC)C=C3)C=C2)=CS1

Molecular Formula

C17H16N2OS

Molecular Weight

296.39

References & Citations

[1]Ahmad H, et, al. A combine approach of chemical synthesis, biological evaluation and structural dynamics studies revealed thiazole substituted arylamine derivatives as potent FabH enzyme inhibitors. Bioorg Chem. 2020 Dec;105:104426.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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