FabH-IN-1
FabH-IN-1 (compound 3f) is an inhibitor of bacterial 3-oxoacyl-[acyl-carrier-protein] synthase 3 (FabH) enzyme which is a broad-spectrum antimicrobial target. FabH-IN-1 is effective against gram-positive and gram-negative. FabH-IN-1 is also a good antioxidant[1].
Product Specifications
CAS Number
2692652-49-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fabh-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=NC(C2=CC=C(NC3=CC=C(OC)C=C3)C=C2)=CS1
Molecular Formula
C17H16N2OS
Molecular Weight
296.39
References & Citations
[1]Ahmad H, et, al. A combine approach of chemical synthesis, biological evaluation and structural dynamics studies revealed thiazole substituted arylamine derivatives as potent FabH enzyme inhibitors. Bioorg Chem. 2020 Dec;105:104426.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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