Anticancer agent 69
Product Specifications
UNSPSC Description
Anticancer agent 69 (Compound 34), a potent and selective anticancer agent?, potently and selectively inhibits human?prostate cancer?cell line PC3 (IC50=26 nM). Anticancer agent 69?increases?ROS?level, down-regulates?EGFR?and induces apoptosis[1].
Target Antigen
Apoptosis; EGFR; Reactive Oxygen Species
Type
Reference compound
Related Pathways
Apoptosis;Immunology/Inflammation;JAK/STAT Signaling;Metabolic Enzyme/Protease;NF-κB;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-69.html
Solubility
10 mM in DMSO
Smiles
[H]/C(C1=CC=CC=N1)=N\NC2=NC(SCCC)=NC3=C2N=NN3CCCCCC
Molecular Weight
398.53
References & Citations
[1]Chenhao Xu, et al. Novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing hydrazone fragment as potent and selective anticancer agents. Bioorg Chem. 2020 Dec;105:104424.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146170/Anticancer-agent-69-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146170/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
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