EphA2 agonist 2

EphA2 agonist 2 (Lead compound) is a selective EphA2 agonist with antitumor activities. EphA2 agonist 2 can cross the BBB[1].

Product Specifications

CAS Number

2169273-66-7

UNSPSC

12352005

Target

Ephrin Receptor

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/epha2-agonist-2.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)CCCCCCCCCCC(N4CCN(C5=NC(N)=C6C=C(OC)C(OC)=CC6=N5)CC4)=O

Molecular Formula

C40H56N10O6

Molecular Weight

772.94

References & Citations

[1]Orahoske CM, et al. Dimeric small molecule agonists of EphA2 receptor inhibit glioblastoma cell growth. Bioorg Med Chem. 2020 Sep 15;28 (18) :115656.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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