Transthyretin-IN-1
Transthyretin-IN-1 (Compound 1d) is a transthyretin (TTR) fibril formation inhibitor. Transthyretin-IN-1 can be used for Alzheimer’s disease research[1].
Product Specifications
UNSPSC
12352005
Target
Transthyretin (TTR)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/transthyretin-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCO/N=C/C1=CC(Br)=CC(Br)=C1O
Molecular Formula
C10H9Br2NO4
Molecular Weight
366.99
References & Citations
[1]Ciccone L, et al. Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis. Bioorg Med Chem. 2020 Sep 15;28 (18) :115673.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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