Transthyretin-IN-1

Transthyretin-IN-1 (Compound 1d) is a transthyretin (TTR) fibril formation inhibitor. Transthyretin-IN-1 can be used for Alzheimer’s disease research[1].

Product Specifications

UNSPSC

12352005

Target

Transthyretin (TTR)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/transthyretin-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CCO/N=C/C1=CC(Br)=CC(Br)=C1O

Molecular Formula

C10H9Br2NO4

Molecular Weight

366.99

References & Citations

[1]Ciccone L, et al. Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis. Bioorg Med Chem. 2020 Sep 15;28 (18) :115673.