Aldose reductase-IN-5
As an aldose reductase (ALR2) inhibitor, the compound is used to enhance the combination of inhibitory excitability and antioxidant capacity to delay the progress of diabetes complications.
Product Specifications
CAS Number
[2480090-03-5]
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/aldose-reductase-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CN1CC(OC2=C(/C=C/C3=CC=C(O)C=C3)C=CC=C12)=O
Molecular Formula
C18H15NO5
Molecular Weight
325.32
References & Citations
[1]Chen H, et al. Dihydrobenzoxazinone derivatives as aldose reductase inhibitors with antioxidant activity. Bioorg Med Chem. 2020 Oct 15;28 (20) :115699.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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