Aldose reductase-IN-5

As an aldose reductase (ALR2) inhibitor, the compound is used to enhance the combination of inhibitory excitability and antioxidant capacity to delay the progress of diabetes complications.

Product Specifications

CAS Number

[2480090-03-5]

UNSPSC

12352005

Target

Aldose Reductase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/aldose-reductase-in-5.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CN1CC(OC2=C(/C=C/C3=CC=C(O)C=C3)C=CC=C12)=O

Molecular Formula

C18H15NO5

Molecular Weight

325.32

References & Citations

[1]Chen H, et al. Dihydrobenzoxazinone derivatives as aldose reductase inhibitors with antioxidant activity. Bioorg Med Chem. 2020 Oct 15;28 (20) :115699.