ATX inhibitor 19
ATX inhibitor 19 (compound 22) is a potent ATX (autotaxin) inhibitor, with an IC50 of 156 nM[1].
Product Specifications
CAS Number
2691937-01-4
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atx-inhibitor-19.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CN(CC)C2=C1C=C(C3=NC(CN4CCN(CCO)CC4)=CS3)C=C2)NCC5=CC=C(Cl)C=C5
Molecular Formula
C28H33ClN6O2S
Molecular Weight
553.12
References & Citations
[1]Jia F, et al. Structure-based linker exploration: Discovery of 1-ethyl-1H-indole analogs as novel ATX inhibitors. Bioorg Med Chem. 2020 Nov 15;28 (22) :115795.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Autotaxin
Frequently Asked Questions
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