Antitubercular agent-26
Antitubercular agent-26 (Compound 32) is an orally active anti-tubercular agent with an extracellular IC50 of 0.50 μM and an intracellular IC50 of 0.51 μM against M. tuberculosis H37Rv. Antitubercular agent-26 shows good metabolic stability, low risk of cardiotoxicity and no genotoxicity[1].
Product Specifications
CAS Number
1845720-46-8
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitubercular-agent-26.html
Solubility
10 mM in DMSO
Smiles
O=C(C(S1)=CC2=C1N=C(N3CCC(C(N(C)C)=O)CC3)S2)NC4=CC=C(OC(C)=N5)C5=C4
Molecular Formula
C22H23N5O3S2
Molecular Weight
469.58
References & Citations
[1]Jin G, et al. Discovery of thienothiazolocarboxamide analogues as novel anti-tubercular agent. Bioorg Med Chem. 2020 Dec 1;28 (23) :115797.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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