P-gp modulator 2

P-gp modulator 2 (Compound 27) is a potent, competitive, allosteric P-glycoprotein (P-gp) modulator[1].

Product Specifications

CAS Number

2987145-05-9

UNSPSC

12352005

Target

P-glycoprotein

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/p-gp-modulator-2.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C(C=C1)[C@@H]2C/C(C3=C(O2)C=C(C=C3O)OC)=N\NC4=CC=C(C=N4)Br

Molecular Formula

C22H20BrN3O4

Molecular Weight

470.32

References & Citations

[1]Ferreira RJ, et al. Nitrogen-containing naringenin derivatives for reversing multidrug resistance in cancer. Bioorg Med Chem. 2020 Dec 1;28 (23) :115798.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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