RyRs activator 2

RyRs activator 2 (compound 7o) is a potent activator of ryanodine receptors (RyRs) . RyRs activator 2 is 30% larvicidal activity, comparable to chlorantraniliprole (30%) and better than cyantraniliprole (10%) [1].

Product Specifications

CAS Number

[2408415-52-9]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ryrs-activator-2.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(C(F)(F)F)=NN1C2=CC(C#N)=CC=C2Cl)NC3=C(C(NC(C)C)=O)C=C(Cl)C=C3C

Molecular Formula

C23H18Cl2F3N5O2

Molecular Weight

524.32

References & Citations

[1]Liu J, et al. Discovery of a polysubstituted phenyl containing novel N-phenylpyrazole scaffold as potent ryanodine receptor activator. Bioorg Med Chem. 2020 Dec 15;28 (24) :115829.