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NMDA receptor antagonist 5

NMDA receptor antagonist 5 (Compound 10e) is a potent, brain permeable and non-toxic NMDA receptor antagonist. NMDA receptor antagonist 5 can be used for neurological disorder research[1].

Product Specifications

CAS Number

2415998-36-4

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nmda-receptor-antagonist-5.html

Solubility

10 mM in DMSO

Smiles

O=C1CC[C@]2(C3=CC=C(Br)C=C3)O[C@](CC4=C5C=CC=C4)([H])[C@]5([H])N21

Molecular Formula

C19H16BrNO2

Molecular Weight

370.24

References & Citations

[1]Espadinha M, et al. Identification of tetracyclic lactams as NMDA receptor antagonists with potential application in neurological disorders. Eur J Med Chem. 2020 May 15;194:112242.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NMDA Receptor

Frequently Asked Questions

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