HIV-1 inhibitor-33
HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor with an EC50 of 8.6 nM for HIV-1 and a CC50 of 18 μM in MT-4 cells. HIV-1 inhibitor-33 can be used for researching AIDS[1].
Product Specifications
CAS Number
[2395777-43-0]
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-33.html
Solubility
10 mM in DMSO
Smiles
CC(C=CC=C1C)=C1OC2=CC=NC(NC3CCN(CC3)CC4=NNC5=C4C=CC=C5)=N2
Molecular Formula
C25H28N6O
Molecular Weight
428.53
References & Citations
[1]Xiao T, et al. Indazolyl-substituted piperidin-4-yl-aminopyrimidines as HIV-1 NNRTIs: Design, synthesis and biological activities. Eur J Med Chem. 2020;186:111864.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
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