HIV-1 inhibitor-33

HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor with an EC50 of 8.6 nM for HIV-1 and a CC50 of 18 μM in MT-4 cells. HIV-1 inhibitor-33 can be used for researching AIDS[1].

Product Specifications

CAS Number

[2395777-43-0]

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hiv-1-inhibitor-33.html

Solubility

10 mM in DMSO

Smiles

CC(C=CC=C1C)=C1OC2=CC=NC(NC3CCN(CC3)CC4=NNC5=C4C=CC=C5)=N2

Molecular Formula

C25H28N6O

Molecular Weight

428.53

References & Citations

[1]Xiao T, et al. Indazolyl-substituted piperidin-4-yl-aminopyrimidines as HIV-1 NNRTIs: Design, synthesis and biological activities. Eur J Med Chem. 2020;186:111864.