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L-Glutamic acid-13C2

L-Glutamic acid-13C2 is the 13C labeled L-Glutamic acid[1]. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA) . L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[2].

Product Specifications

CAS Number

115473-56-8

UNSPSC

12352211

Target

Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/l-glutamic-acid-13c2.html

Purity

99.7

Solubility

10 mM in DMSO

Smiles

OC(CC[13C@H](N)[13C](O)=O)=O

Molecular Formula

C3 13C2H9NO4

Molecular Weight

149.11

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6 (1) :73-7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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