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CD22 ligand-1

CD22 ligand-1 (compound 12) is a potent and selective CD22 ligand with KD of 0.335, 30.7 µM for hCD22 and MAG, respectively. CD22 ligand-1 has the potential for the research of B-cell related disease[1].

Product Specifications

CAS Number

2493080-27-4

UNSPSC

12352005

Target

CD22

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cd22-ligand-1.html

Solubility

10 mM in DMSO

Smiles

O=C([C@]1(N2C=C(C3=CC=CC=C3)N=N2)O[C@@]([C@@H]([C@H](C1)O)NC(CO)=O)([H])[C@H](O)[C@H](O)CNC(CC4=CC=C(C5=CC=C(C=C5)O)C=C4)=O)O[Na]

Molecular Formula

C33H34N5NaO10

Molecular Weight

683.64

References & Citations

[1]Abdu-Allah HHM, et al. Design, synthesis and molecular docking study of α-triazolylsialosides as non-hydrolyzable and potent CD22 ligands. Eur J Med Chem. 2020 Dec 15;208:112707.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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