Antifungal agent 31
Antifungal agent 31 (compound 12) is a potent and orally active triazole antifungal agents with a pyrrolotriazinone scaffold. Antifungal agent 31 shows antifungal activity against Candida spp. and filamentous fungi. Antifungal agent 31 significantly reduced mortality rates and kidney fungal burden in two murine models of lethal systemic infections[1].
Product Specifications
CAS Number
2077083-94-2
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antifungal-agent-31.html
Solubility
10 mM in DMSO
Smiles
O=C1N([C@H](C)[C@@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3)N=CC4=CC(C5=CC=C(OC)C=C5)=CN14
Molecular Formula
C25H22F2N6O3
Molecular Weight
492.48
References & Citations
[1]Montoir D, et al. New azole antifungals with a fused triazinone scaffold. Eur J Med Chem. 2020 Mar 1;189:112082.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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