Antimicrobial agent-1
Antimicrobial agent-1 (compound 6C) possesses potent activity against TolC mutant E. coli with an MIC value of 2 μg/mL. Antimicrobial agent-1 and Colistin exhibit synergistic activity against Gram-negative bacteria. Antimicrobial agent-1 has no cytotoxicity on mammalian cell lines, with MICs > 128 μg/mL in Caco-2 and Vero cell lines[1].
Product Specifications
CAS Number
[2579696-45-8]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimicrobial-agent-1.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(NC1=CC=CC(C2=NC3=CC=CC=C3N2CC4=CC=C(C)C=C4)=C1)=O
Molecular Formula
C22H21N3O2S
Molecular Weight
391.49
References & Citations
[1]Dokla EME, et al. Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria. Eur J Med Chem. 2020;186:111850.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
U1500-70B-ML650 100 µL
ULK1, ID (Serine/Threonine-protein Kinase ULK1, Unc-51-like Kinase 1, ATG1, KIAA0722) (MaxLight 650) discontinued
Ask
View Details 
GTR15084254 1 Vial
Lentiviral human ABHD16B shRNA (UAS) - Lentiviral human ABHD16B shRNA (UAS, iRFP) (25)
Ask
View Details 244299-ML550 100 µL
CCL13 (Chemokine (C-C Motif) Ligand 13, CKb10, MCP-4, MGC17134, NCC-1, NCC1, SCYA13, SCYL1) (MaxLight 550)
Ask
View Details MBS9349734 Inquire
Pigeon Sodium Channel Protein Type 9 Subunit Alpha (SCN9A) ELISA Kit
Ask
View Details