AEP-IN-1
AEP-IN-1 (Compound 13e) is a CNS agent-like non-covalent inhibitor of asparagine endopeptidase (AEP), with the IC50 of 89 nM. AEP-IN-1 can be used for the research of numerous neurological diseases such as Alzheimer’s disease (AD) [1].
Product Specifications
CAS Number
3032742-75-6
UNSPSC
12352005
Target
Cathepsin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aep-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1CCN(C2=CC(N3CCOCC3)=CC=C2N)CC1)OCC
Molecular Formula
C18H27N3O3
Molecular Weight
333.43
References & Citations
[1]Lorenzo Calugi, et al. Modular synthesis of 2,4-diaminoanilines as CNS drug-like non-covalent inhibitors of asparagine endopeptidase. Bioorg Med Chem. 2022 Jun 1;63:116746.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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