β-Nor-lapachone

β-Nor-lapachone is a Candida glabrata antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity[1].

Product Specifications

CAS Number

[52436-88-1]

UNSPSC

12352005

Target

Fungal; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/β-nor-lapachone.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C2OC(C)(C)C1)C(C3=C2C=CC=C3)=O

Molecular Formula

C14H12O3

Molecular Weight

228.24

References & Citations

[1]Clemente de Moraes D, et al. Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata. Bioorg Med Chem. 2022;63:116749.