β-Nor-lapachone
β-Nor-lapachone is a Candida glabrata antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity[1].
Product Specifications
CAS Number
52436-88-1
UNSPSC
12352005
Target
Fungal; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/β-nor-lapachone.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2OC(C)(C)C1)C(C3=C2C=CC=C3)=O
Molecular Formula
C14H12O3
Molecular Weight
228.24
References & Citations
[1]Clemente de Moraes D, et al. Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata. Bioorg Med Chem. 2022;63:116749.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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