Rasagiline-13C3 (mesylate)
Rasagiline-13C3 ((R) -AGN1135-13C3; TVP1012-13C3) mesylate is the deuterium labeled Rasagiline (mesylate) (HY-14605) [1]. Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively[2].
Product Specifications
CAS Number
[1391052-18-8]
Product Name Alternative
(R) -AGN1135-13C3 (mesylate) ; TVP1012-13C3 (mesylate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Isotope-Labeled Compounds; Monoamine Oxidase
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Autophagy; Neuronal Signaling; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rasagiline-13c3-mesylate.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(O)=O.[13CH]#[13C][13CH2]N[C@H]1C2=CC=CC=C2CC1
Molecular Formula
C10 13C3H17NO3S
Molecular Weight
270.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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