CXCR4 modulator-2
Product Specifications
UNSPSC Description
CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model[1].
Target Antigen
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cxcr4-modulator-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1CCN(C(CCN2C=CC3=C2C=NC=C3)=O)CC1)[C@H](N)CCCNC(N)=N
Molecular Weight
428.53
References & Citations
[1]Oum YH, et al. Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design. Eur J Med Chem. 2020;201:112479.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146054/CXCR4-modulator-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146054/
Clinical Information
No Development Reported
CAS Number
2488943-55-9
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