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CXCR4 modulator-2

CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model[1].

Product Specifications

CAS Number

[2554877-43-7]

UNSPSC

12352005

Target

CXCR

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cxcr4-modulator-2.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1CCN(C(CCN2C=CC3=C2C=NC=C3)=O)CC1)[C@@H](N)CCCNC(N)=N

Molecular Formula

C21H32N8O2

Molecular Weight

428.53

References & Citations

[1]Oum YH, et al. Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design. Eur J Med Chem. 2020;201:112479.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-146054/CXCR4-modulator-2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-146054/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CXCR4

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