Antitumor agent-57
Antitumor agent-57 (Compound 3o) is an NQO1-directed antitumor agent. Antitumor agent-57 inhibits tumor cell growth, triggers ROS generation and induces cell apoptosis[1].
Product Specifications
CAS Number
2432823-48-6
UNSPSC
12352005
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-57.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=C(C(C(C3=CC=CC=C32)=O)=O)C(C4=CC=C(OC)C(O)=C4)C1
Molecular Formula
C20H15NO5
Molecular Weight
349.34
References & Citations
[1]Wu LQ, et al. Design, synthesis, and biological evaluation of 4-substituted-3,4-dihydrobenzo[h]quinoline-2,5,6 (1H) -triones as NQO1-directed antitumor agents. Eur J Med Chem. 2020 Jul 15;198:112396.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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