Antitumor agent-56
Product Specifications
UNSPSC Description
Antitumor agent-56 (Compound 33) is a triptolide derivative with antitumor, anti-inflammatory and NO release activities. Antitumor agent-56 significantly inhibits the growth of melanoma. Antitumor agent-56 is orally active[1].
Target Antigen
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-56.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@@]34[C@@]5([C@@](C[C@@]1([H])C6=C(C(OC6)=O)CC2)([H])O5)[C@@H]([C@@]7([C@](O7)([H])[C@]3([H])O4)C(C)C)OC8=NO[N+]([O-])=C8S(=O)(C9=CC=CC=C9)=O
Molecular Weight
584.59
References & Citations
[1]Zang Y, et al. Novel nitric oxide-releasing derivatives of triptolide as antitumor and anti-inflammatory agents: Design, synthesis, biological evaluation, and nitric oxide release studies. Eur J Med Chem. 2020 Mar 15;190:112079.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146046/Antitumor-agent-56-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146046/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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