Antiparasitic agent-6

Antiparasitic agent-6 (compound 5b) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 3.89 μM. Antiparasitic agent-6 also has certain cytotoxicity against HepG2 (CC50 = 13.64 μM) [1].

Product Specifications

CAS Number

[2253996-73-3]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antiparasitic-agent-6.html

Solubility

10 mM in DMSO

Smiles

N#CC1=CC=C(C(O)C(C2=NC(C3=CC=C(OC)C=C3)=NO2)=C)C=C1

Molecular Formula

C19H15N3O3

Molecular Weight

333.34

References & Citations

[1]Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.