Antiparasitic agent-5
Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC50 = 6.78 μM) [1].
Product Specifications
CAS Number
2494276-55-8
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antiparasitic-agent-5.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CC)C2=C(C=C(Cl)C=C2)C1(O)C(C3=NC(C4=CC=CC=C4)=NO3)=C
Molecular Formula
C20H16ClN3O3
Molecular Weight
381.81
References & Citations
[1]Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania
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