Antiparasitic agent-2
Product Specifications
UNSPSC Description
Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM)[1].
Target Antigen
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antiparasitic-agent-2.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CC)C2=C(C=CC=C2)C1(O)C(C3=NC(C4=CC=CC=C4)=NO3)=C
Molecular Weight
347.37
References & Citations
[1]Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146041/Antiparasitic-agent-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146041/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
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