AChE-IN-15
Product Specifications
UNSPSC Description
AChE-IN-15 (Compound 3d) is a reversible human acetylcholinesterase (huAChE) (IC50=6.8 μM) and human butyrylcholinesterase (huBChE) (IC50=16.1 μM) inhibitor. AChE-IN-15 shows significant antioxidant potency, AChE-IN-15 can be used for the research of Alzheimer’s disease[1].
Target Antigen
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-15.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1=CC=C(C2=CC(C3=C(O)C=C(OC(N(CC)C)=O)C=C3O2)=O)C=C1)N(CC)C
Molecular Weight
440.45
References & Citations
[1]Zhipei Sang, et al. Apigenin-rivastigmine hybrids as multi-target-directed liagnds for the treatment of Alzheimer's disease. Eur J Med Chem. 2020 Feb 1;187:111958.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146039/AChE-IN-15-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146039/
Clinical Information
No Development Reported
CAS Number
2242792-25-0
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