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Multi-kinase-IN-1

Multi-kinase-IN-1 (Compound 11k) is a potent kinase inhibitor with antitumor activity. Multi-kinase-IN-1 induces cell apoptosis, and can be studied for colorectal cancer[1].

Product Specifications

CAS Number

2470807-67-9

UNSPSC

12352005

Target

Apoptosis; c-Met/HGFR; PDGFR; Src; TAM Receptor

Type

Reference compound

Related Pathways

Apoptosis; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/multi-kinase-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCC(OC2=C(OC)C=C3C(OC4=CC=C(NC(NN5C(C6=C(F)C=CC=C6F)SCC5=O)=O)C=C4)=CC=NC3=C2)CC1)NC(C)C

Molecular Formula

C35H36F2N6O6S

Molecular Weight

706.76

References & Citations

[1]Yuting Zhou, et al. Identification of novel quinoline analogues bearing thiazolidinones as potent kinase inhibitors for the treatment of colorectal cancer. Eur J Med Chem. 2020 Oct 15;204:112643.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDGFRα

Frequently Asked Questions

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