AL-470

AL-470 is a potent antiviral agent with EC50 values of 0.27, 0.63, and 0.35 μM against HIV-1, HIV-2, and EV-A71, respectively[1].

Product Specifications

CAS Number

[2671019-15-9]

UNSPSC

12352005

Target

Enterovirus; HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/al-470.html

Solubility

10 mM in DMSO

Smiles

OC(C1=CC(C(O)=O)=CC(C(NC2=CC=CC=C23)=C3C[C@@H](C(O)=O)NC(CCC(CCC(N[C@H](C(O)=O)CC4=C(C5=CC(C(O)=O)=CC(C(O)=O)=C5)NC6=CC=CC=C64)=O)([N+]([O-])=O)CCC(N[C@H](C(O)=O)CC7=C(C8=CC(C(O)=O)=CC(C(O)=O)=C8)NC9=CC=CC=C97)=O)=O)=C1)=O

Molecular Formula

C67H57N7O23

Molecular Weight

1328.20

References & Citations

[1]Olaia Martí-Marí, et al. Organotropic dendrons with high potency as HIV-1, HIV-2 and EV-A71 cell entry inhibitors. Eur J Med Chem. 2022 Jul 5;237:114414.