HCAIX-IN-17
HCA IX-IN-1 (Compound 6f) is a human carbonic anhydrase (hCA) inhibitor with Ki values of 331.4, 28.4, 9.4 and 17.8 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-1 shows anticancer activity[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hca-ix-in-1.html
Solubility
10 mM in DMSO
Smiles
NS(=O)(C1=CC=C(C=C1)NCCC(C2=CC3=C(C=C2)C=CC=C3)=O)=O
Molecular Formula
C19H18N2O3S
Molecular Weight
354.42
References & Citations
[1]Elbadawi MM, et al. Development of 4- ((3-oxo-3-phenylpropyl) amino) benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2022 Apr 27;238:114412.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II; CA IX; CA XII
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