FAAL-IN-1

FAAL-IN-1 (compound 32) is a selective inhibitor of fatty acyl-AMP ligase (FAAL), with a Ki of 0.7 μM for FAAL28. FAAL-IN-1 shows antimycobacterial activity[1].

Product Specifications

CAS Number

[1965250-07-0]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/faal-in-1.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@](O[C@@H]([C@H]1O)COS(NC(CCCCCCCCCCOC2=CC=CC=C2)=O)(=O)=O)([H])N3C4=NC=NC(N)=C4N=C3

Molecular Formula

C27H38N6O8S

Molecular Weight

606.69

References & Citations

[1]Baran M, et, al. Development of small-molecule inhibitors of fatty acyl-AMP and fatty acyl-CoA ligases in Mycobacterium tuberculosis. Eur J Med Chem. 2020 Sep 1;201:112408.