Influenza virus-IN-3
Influenza virus-IN-3 (compound 9) is a potent and selective influenza virus inhibitor with IC50s of 0.88, 0.10, 5.5, 0.51 μM for H5N1, H5N2, H5N6, H5N8, respectively. Influenza virus-IN-3 shows antiviral and NA (neuraminidase enzyme) -inhibitory activity. Influenza virus-IN-3 shows low cytotoxicity with an CC50 of >200 μM[1].
Product Specifications
CAS Number
2412451-16-0
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/influenza-virus-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](NCC2=CC=C(C3=CSC=C3)C=C2)C1)O
Molecular Formula
C25H32N2O4S
Molecular Weight
456.60
References & Citations
[1]Ai W, et al. Discovery of novel "Dual-site" binding oseltamivir derivatives as potent influenza virus neuraminidase inhibitors. Eur J Med Chem. 2020 Apr 1;191:112147.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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