STC314
STC314 is a small polyanion that interact electrostatically with histones. STC314 blocks disruption of lipid-bilayers by histones that inhibits the cytotoxic, platelet-activating and erythrocyte-damaging effects of histones. STC314 has anti-infective effects and can be uesd for sepsis research[1].
Product Specifications
CAS Number
401513-39-1
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/stc314.html
Solubility
10 mM in DMSO
Smiles
O=[S](O[C@H]([C@H]1O[S](=O)(O[Na])=O)[C@@H]([C@H](O[C@H]1OC)CO[S](=O)(O[Na])=O)O[C@H](O[C@@H]2CO[S](=O)(O[Na])=O)[C@@H]([C@H]([C@@H]2O[S](=O)(O[Na])=O)O[S](=O)(O[Na])=O)O[S](=O)(O[Na])=O)(O[Na])=O
Molecular Formula
C13H17Na7O32S7
Molecular Weight
1070.64
References & Citations
[1]Connor H O' Meara, et al. Neutralizing the pathological effects of extracellular histones with small polyanions. Nat Commun. 2020 Dec 16;11 (1) :6408.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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