CBR-3465
CBR-3465 is a mycobacterium tuberculosis (Mtb) type II NADH dehydrogenase inhibitor, with the MIC of 0.16 μM against Mtb[1].
Product Specifications
CAS Number
2225883-59-8
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cbr-3465.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C(NC2=C1C(F)=CC=C2)SCC(NC3CCCCC3)=O
Molecular Formula
C16H18FN3O2S
Molecular Weight
335.40
References & Citations
[1]Harbut MB, et, al. Small Molecules Targeting Mycobacterium tuberculosis Type II NADH Dehydrogenase Exhibit Antimycobacterial Activity. Angew Chem Int Ed Engl. 2018 Mar 19;57 (13) :3478-3482.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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