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CBR-3465

CBR-3465 is a mycobacterium tuberculosis (Mtb) type II NADH dehydrogenase inhibitor, with the MIC of 0.16 μM against Mtb[1].

Product Specifications

CAS Number

2225883-59-8

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cbr-3465.html

Solubility

10 mM in DMSO

Smiles

O=C1N=C(NC2=C1C(F)=CC=C2)SCC(NC3CCCCC3)=O

Molecular Formula

C16H18FN3O2S

Molecular Weight

335.40

References & Citations

[1]Harbut MB, et, al. Small Molecules Targeting Mycobacterium tuberculosis Type II NADH Dehydrogenase Exhibit Antimycobacterial Activity. Angew Chem Int Ed Engl. 2018 Mar 19;57 (13) :3478-3482.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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