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M7GpppCpG

M7GpppCpG, an oligonucleotide, is an M7GpppNpG trinucleotide cap analogue. m7GpppCpG can be used as a chemical tool enabling manufacturing of RNA featuring either cap 0 or cap 1 structures[1].

Product Specifications

CAS Number

2638447-78-4

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/m7gpppcpg.html

Solubility

10 mM in DMSO

Smiles

O=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(NC(N)=NC4=O)=C4N=C3)O2)=O)[C@@H](O)[C@H](N5C(N=C(N)C=C5)=O)O1)OP(OP(OC[C@@H]6[C@@H](O)[C@@H](O)[C@H](N7C(NC(N)=NC8=O)=C8[N+](C)=C7)O6)([O-])=O)(O)=O

Molecular Formula

C30H41N13O25P4

Molecular Weight

1107.61

References & Citations

[1]Sikorski PJ, et, al. The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5' cap modulates protein expression in living cells. Nucleic Acids Res. 2020 Feb 28;48 (4) :1607-1626.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Frequently Asked Questions

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