m7GpppUpG
Product Specifications
UNSPSC Description
m7GpppUpG, an oligonucleotide, is an M7GpppNpG trinucleotide cap analogue. m7GpppUpG can be used as a chemical tool enabling manufacturing of RNA featuring either cap 0 or cap 1 structures[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/m7gpppupg.html
Solubility
10 mM in DMSO
Smiles
O=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(NC(N)=NC4=O)=C4N=C3)O2)=O)[C@@H](O)[C@H](N5C(NC(C=C5)=O)=O)O1)OP(OP(OC[C@@H]6[C@@H](O)[C@@H](O)[C@H](N7C(NC(N)=NC8=O)=C8[N+](C)=C7)O6)([O-])=O)(O)=O
Molecular Weight
1108.60
References & Citations
[1]Sikorski PJ, et, al. The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5' cap modulates protein expression in living cells. Nucleic Acids Res. 2020 Feb 28;48(4):1607-1626.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145980/m7GpppUpG-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145980/
Clinical Information
No Development Reported
CAS Number
2638447-85-3
Curated Selection
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