M7GpppUmpG
M7GpppUmpG, an oligonucleotide, is an M7GpppNpG trinucleotide cap analogue. m7GpppUmpG can be used as a chemical tool enabling manufacturing of RNA featuring either cap 0 or cap 1 structures[1].
Product Specifications
CAS Number
2638447-87-5
UNSPSC
12352208
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/m7gpppumpg.html
Solubility
10 mM in DMSO
Smiles
O=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(NC(N)=NC4=O)=C4N=C3)O2)=O)[C@@H](OC)[C@H](N5C(NC(C=C5)=O)=O)O1)OP(OP(OC[C@@H]6[C@@H](O)[C@@H](O)[C@H](N7C(NC(N)=NC8=O)=C8[N+](C)=C7)O6)([O-])=O)(O)=O
Molecular Formula
C31H42N12O26P4
Molecular Weight
1122.63
References & Citations
[1]Sikorski PJ, et, al. The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5' cap modulates protein expression in living cells. Nucleic Acids Res. 2020 Feb 28;48 (4) :1607-1626.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
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