M7GpppGmpG

M7GpppGmpG is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86%[1].

Product Specifications

CAS Number

[1258049-00-1]

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/m7gpppgmpg.html

Solubility

10 mM in DMSO

Smiles

O=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@H]2O[C@@H](N3C(NC(N)=NC4=O)=C4N=C3)[C@H](O)[C@@H]2O)=O)[C@@H](OC)[C@H](N5C(NC(N)=NC6=O)=C6N=C5)O1)OP(OP(OC[C@H]7O[C@@H](N8C(NC(N)=N9)=C([N+](C)=C8)C9=O)[C@H](O)[C@@H]7O)([O-])=O)(O)=O

Molecular Formula

C32H43N15O25P4

Molecular Weight

1161.66

References & Citations

[1]Sikorski PJ, et, al. The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5' cap modulates protein expression in living cells. Nucleic Acids Res. 2020 Feb 28;48 (4) :1607-1626.