MC-Val-Cit-PAB-Amide-TLR7 agonist 4
MC-Val-Cit-PAB-Amide-TLR7 agonist 4 (example 15) is a HER2-TLR7 and HER2-TLR8 immune agonist conjugate[1].
Product Specifications
CAS Number
[2413016-49-4]
UNSPSC
12352005
Target
EGFR; Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mc-val-cit-pab-amide-tlr7-agonist-4.html
Purity
99.39
Solubility
10 mM in DMSO
Smiles
O=C(C=CC1=O)N1CCCCCC(N[C@H](C(N[C@H](C(NC2=CC=C(COC(NC(C)(C)C(NCCOC(C)(C)CN3C(C4=CC=CC=C4N=C5N)=C5N=C3COCC)=O)=O)C=C2)=O)CCCNC(N)=O)=O)C(C)C)=O
Molecular Formula
C52H72N12O11
Molecular Weight
1041.20
References & Citations
[1]Valerie Odegard, et al. Compositions for the treatment of disease with immune stimulatory conjugates. WO2020056008 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ErbB2/HER2; TLR7; TLR8
Available Sizes
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