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MC-Val-Cit-PAB-Amide-TLR7 agonist 4

MC-Val-Cit-PAB-Amide-TLR7 agonist 4 (example 15) is a HER2-TLR7 and HER2-TLR8 immune agonist conjugate[1].

Product Specifications

CAS Number

[2413016-49-4]

UNSPSC

12352005

Target

EGFR; Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mc-val-cit-pab-amide-tlr7-agonist-4.html

Purity

99.39

Solubility

10 mM in DMSO

Smiles

O=C(C=CC1=O)N1CCCCCC(N[C@H](C(N[C@H](C(NC2=CC=C(COC(NC(C)(C)C(NCCOC(C)(C)CN3C(C4=CC=CC=C4N=C5N)=C5N=C3COCC)=O)=O)C=C2)=O)CCCNC(N)=O)=O)C(C)C)=O

Molecular Formula

C52H72N12O11

Molecular Weight

1041.20

References & Citations

[1]Valerie Odegard, et al. Compositions for the treatment of disease with immune stimulatory conjugates. WO2020056008 A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ErbB2/HER2; TLR7; TLR8

Available Sizes

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