NAT2-IN-1
NAT2-IN-1 (APA) is an inhibitor of agent metabolic enzyme N-acetyltransferase 2 (NAT2) . NAT2-IN-1 can selectively kill slow NAT2 cells[1].
Product Specifications
CAS Number
[856005-97-5]
Product Name Alternative
APA
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nat2-in-1.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
COC1=C(OC)C(OC)=CC(NC2=NC(C3=CC=C(N)C=C3)=CN=C2)=C1
Molecular Formula
C19H20N4O3
Molecular Weight
352.39
Precautions
H315, H319, H335
References & Citations
[1]Rendo V, et, al. Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy. Nat Commun. 2020 Mar 11;11 (1) :1308.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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