M7GpppApG

M7GpppApG is a trinucleotide mRNA 5' cap analog that can be used for RNA synthesis in vitro[1].

Product Specifications

CAS Number

[80010-97-5]

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/m7gpppapg.html

Solubility

10 mM in H2O

Smiles

O=P(O)(OC[C@H]1[C@H](OP(O)(OC[C@H]2O[C@@H](N3C(NC(N)=NC4=O)=C4N=C3)[C@H](O)[C@@H]2O)=O)[C@@H](O)[C@H](N5C=NC6=C(N)N=CN=C65)O1)OP(OP(OC[C@H]7O[C@@H](N8C(NC(N)=N9)=C([N+](C)=C8)C9=O)[C@H](O)[C@@H]7O)([O-])=O)(O)=O

Molecular Formula

C31H41N15O24P4

Molecular Weight

1131.64

References & Citations

[1]Sikorski PJ, Warminski M, Kubacka D, et al. The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5' cap modulates protein expression in living cells. Nucleic Acids Res. 2020;48 (4) :1607-1626.