NLRP3-IN-6
NLRP3-IN-6 (Compound 34) is a selective NLRP3 inflammasome inhibitor[1].
Product Specifications
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C(/C(SC1=S)=C/C2=CC=C(C=C2)S(N)(=O)=O)N1CC3=CC(Cl)=CC=C3OC
Molecular Formula
C18H15ClN2O4S3
Molecular Weight
454.97
References & Citations
[1]Zuo D, et al. Design and synthesis of an N-benzyl 5- (4-sulfamoylbenzylidene-2-thioxothiazolidin-4-one scaffold as a novel NLRP3 inflammasome inhibitor. Bioorg Med Chem Lett. 2022 Jun 1;65:128693.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NLRP3
Curated Selection
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