LC kinetic stabilizer-2
LC kinetic stabilizer-2 is a potent amyloidogenic immunoglobulin light chain (LC) kinetic stabilizer with an EC50 of 24 nM[1].
Product Specifications
CAS Number
[2495750-20-2]
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lc-kinetic-stabilizer-2.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2=CC(N(CC)CC)=CC=C2C(C)=C1CCNC(NCC3=CC(C=CC=C4)=C4C=C3)=O
Molecular Formula
C28H31N3O3
Molecular Weight
457.56
References & Citations
[1]Nicholas L Yan, et al. Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site. Bioorg Med Chem Lett. 2022 Mar 15;60:128571.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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