Anti-inflammatory agent 12
Anti-inflammatory agent 12 (Compound 2) is a pentacyclic triterpene compound. Anti-inflammatory agent 12 shows a significant bias in the LPS-induced inflammatory response with an IIC50 value of 2.22 μM. Anti-inflammatory agent 12 has the potential for the research of inflammation disease[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352211
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-12.html
Solubility
10 mM in DMSO
Smiles
[H][C@]12C3C=C[C@@]4([C@]5(CC[C@@H](C(C)(C5C[C@@H]([C@]4([C@@]3(CC[C@]1(C[C@@H]([C@H]([C@@H]2C)C)O)CO)C)C)O)C)O)C)[H]
Molecular Formula
C30H50O4
Molecular Weight
474.72
References & Citations
[1]Jiang X, et al. Microbial transformation and inhibitory effect assessment of uvaol derivates against LPS and HMGB1 induced NO production in RAW264.7 macrophages. Bioorg Med Chem Lett. 2022;58:128523.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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